Yet another CRISPR meeting?

Not exactly.

Our aim is to directly empower you to use the CRISPR technology more effectively in your work. Last year, Genome Engineering 4.0 was a great success in allowing us to share our practical experience in person (rather than just online) and highlight cutting edge advances in genome editing technology and application. Genome Engineering 5.0 follows on that tradition with a peer-to-peer workshop May 7th and talks describing some of the most exciting developments in the field on May 8th and 9th.

You will get to hear about recent developments in CRISPR-based genome editing, from improved specificity to novel applications, and have opportunities to meet with experts with hands-on experience in a range of areas. In addition, you'll have a chance to present your own CRISPR work! Selected abstracts will be chosen for short talks, and there will be a poster session so you can get feedback from colleagues and leading figures in the field.

Come to:
  • learn about the design, implementation, and analysis of CRISPR experiments;
  • discuss latest technical advances and share ideas;
  • troubleshoot your experiments;
  • explore diverse applications of CRISPR nucleases;
  • get answers to your questions, both general and specific.

GE5.0 Program

This workshop is a collaboration between many of the labs developing CRISPR genome engineering.

Keynote speakers:

Eugene Koonin, NCBI & Jim Wilson, UPenn

You will receive practical advice on:
  • Basics of targeted mutagenesis
  • High throughput applications and data analysis
  • Pooled knockout screens
  • Understanding specificity and off-target effects
  • Analysis of targeting efficiency and off-target events
  • Genome-scale transcriptional control
  • Editing of iPSCs, ESCs, and HSCs
  • Making transgenic mice with Cas9
  • In vivo delivery of Cas9
  • Editing in model and non-model organisms
Confirmed GE5.0 Speakers

  • Francesca Storici, Georgia Tech
  • Aaron McKenna, Shendure Lab at University of Washington
  • David Liu, Broad Institute of MIT and Harvard
  • Alex East-Seletsky, Doudna Lab at UC Berkeley
  • Vamsi Mootha, Harvard
  • Kirsten Frieda, Elowitz Lab at CalTech
  • Alan Davidson, University of Toronto
  • Viraj Sanghvi, Wendel Lab at MSKCC
  • Kate O'Connor, University of Wisconsin
  • Ophir Shalem, UPenn
  • Haiyen Jiang, Editas
  • Britt Adamson, Weissman Lab at UCSF
  • Dan Gibson, SGI



Cambridge, MA

The Broad Institute
415 Main St.
Cambridge, MA 02142

Hosted by the Broad Institute



What do I need to do?

Register here!

Can I present my work?

You are encouraged to share your work with your fellow workshop attendees. For this purpose we will have an informal poster session on Monday, May 8. In addition, this year we are choosing four abstracts for selected short talks on Sunday, May 7th, so send us your best work! Abstracts can be submitted via the registration link or email your abstract to by April 10.

Do I need to pay for anything?

Based on the feedback from last year, we will be charging $25 for academic attendees to hold your spot and cover coffee and snacks. Please contact the Workshop Team if you need financial assitance. The rest of the event is made possible by the generosity of the Broad Institute, Addgene, Benchling, Desktop Genetics, and Twist Bioscience.

Can't make it to Cambridge? We will be live-streaming the event. Sign up is free!


Contact Us

If you have any questions, please email us at